Brain fog, other long COVID symptoms focus of new small treatment studies
Scientists don’t yet know what causes long COVID, the catch-all term for about 200 widely varying symptoms.
Medical Research
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Hearing aids could cut risk of cognitive decline by nearly half
A large study showed that older adults with a higher risk of dementia may be able to reduce their risk of cognitive decline by almost 50 percent by using hearing aids.
New research shows Lilly drug slows decline in Alzheimer’s patients
If U.S. regulators approve, the drug would be only the second Alzheimer’s treatment convincingly shown to delay the mind-robbing disease—after rival Leqembi. Both drugs pose a serious safety concern—brain swelling and bleeding.
State medical institute lands $38M grant from feds
The National Institutes of Health awarded the grant to the Indiana Clinical and Translational Sciences Institute, a partnership among Indiana University, Purdue University and University of Notre Dame.
IU med school shuts down research project that used expired supplies on pigs
Fred Cate, IU’s vice president for research, informed federal officials that the research group had “a pattern of non-compliance” and had been warned several times against using expired materials.
IU School of Medicine lands $215M in NIH funding, just shy of another record
Five of the top 10 research studies that received the most NIH funding at the medical school were for Alzheimer’s disease or brain aging, one of the school’s top priorities.
Regenstrief Institute hires epidemiology, research expert as CEO
Dr. Rachel Patzer, director of the Health Services Research Center at the Emory University School of Medicine in Atlanta, will join Regenstrief Institute on May 1.
IU School of Medicine receives grant to study life-threatening heart defects in newborns
Researchers at Indiana University School of Medicine are hoping to gain new insights into the defect, called coarctation of the aorta, or narrowing of the aorta that obstructs blood flow to vital organs.
Diabetes drug Lilly abandoned has new life
In an amazing resurrection, teplizumab, developed by another company after Lilly trials were a letdown, is one of the hottest new drugs on the market.
IU researchers developing virtual-reality tool to treat substance abuse
The high-tech approach allows a patient recovering from substance abuse to interact with potential future versions of himself or herself.
NICO Corp.’s brain surgery tools gain traction, $12.6M in new funding
After 15 years of coaxing and cajoling the medical community to consider a different way to do brain surgery, NICO co-founder Jim Pearson has numbers to show more surgeons and investors are buying into his vision.
Profit, pain and puppies: Inside the rescue of nearly 4,000 beagles
Here’s how beagles being bred for research by an Indianapolis-based company became the target of the largest animal welfare seizure in the Humane Society’s history.
IU medical school wins $49M grant to continue Alzheimer’s studies
The money will be used to study animal models of late-onset Alzheimer’s disease as well as perform rigorous testing of potential therapeutics in animals.
Small cancer drug trial sees tumors disappear in 100% of patients
Researchers in the field of colorectal cancer are hailing the study, published Sunday in the New England Journal of Medicine, as a groundbreaking development that could lead to new treatments for other cancers as well.
Federal judge issues order against research dog-breeding facility
U.S. District Judge Norman Moon said the evidence from federal inspections shows more than 300 beagle puppies have died at the facility, which is owned by Indianapolis-based Envigo, over the last seven months of unknown causes.
Feds sue Indianapolis-based operator of dog-breeding facility, seize beagles
Repeated federal inspections since Envigo acquired the facility have resulted in dozens of violations, including findings that dogs had received inadequate medical care and insufficient food, were housed in filthy conditions, and some had been euthanized without first receiving anesthesia.
Purdue research led to FDA-approved treatment of advanced prostate cancer
Brooke Beier, senior vice president of commercialization at the Purdue Research Foundation, said FDA approval of the therapy is one of the most meaningful approvals ever for a Purdue-related innovation.
Eli Lilly’s Alzheimer’s drug hits roadblock
The FDA has agreed to speed up review of donanemab, but the Centers for Medicare and Medicaid Services is moving to limit reimbursement for drugs in this class to only patients in clinical trials.
Researchers are asking why some countries were better prepared for COVID. One surprising answer: Trust.
“We found no links between COVID outcomes and democracy, populism, government effectiveness, universal health care, pandemic preparedness metrics, economic inequality or trust in science,” a researcher said.
IU-led research shows respiratory disease more common than thought
Data analysis by a team of medical professionals across the country indicates primary ciliary dyskinesia, or PCD, is twice as common as previous estimates, occurring in one of about every 7,500 people.