Q&A: BiomEdit CEO goes behind the scenes of an $18.4M VC round
The animal health startup had fundraising success in 2025, a year in which investment deals were hard to come by.
Startup
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Indianapolis startup Ahimsa growing on the national stage
Founder Dr. Manasa Mantravadi said they’re not stopping with online sales. The Indianapolis pediatrician said the next goal for the company is to have her products in physical stores.
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Growth mindset: How adding staff moves solo entrepreneurs from overwhelmed to opportunity
More than 80% of small businesses in the United States operate without employees, and many entrepreneurs thrive by staying solo. For others, it’s not a sustainable path. But deciding when and how to grow the team can be challenging.
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Lingering conflict means angst for startup community
Indianapolis-based Elevate, a nonprofit venture investment firm, has been operating under a cloud since late April when state officials froze its funding.
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IBJ Podcast: Orr fellows leverage networking to boost value of tech, entrepreneurial positions
Now in its 23rd year, the Orr Fellowship program has helped develop an eye-popping number of leaders in Indiana’s tech and entrepreneurial ecosystems. It now counts 624 alumni who have worked at—and in some cases founded—nearly 300 significant companies and organizations.
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Articles
Indianapolis software firm Opendate lands $14M in growth capital
The company advertises its AI tool as the first of its kind built specifically for managing offers to artists, event details and marketing efforts.
Investors say AI streamlines the work of analyzing deals—but humans still call the shots
Firms locally and nationwide are using AI to help them with everything from researching potential investments to drafting reports to helping them understand complex legal documents.
Crossroads Health Ventures fund secures $21M to support life sciences startups
The fund has secured commitments from Eli Lilly and Co., Corteva Inc., Elanco Animal Health, Indiana University, Parkview Health and the Indiana Economic Development Corp.
Tariff worries spur growth of Indiana life sciences group purchasing program
Participants in the program via the Indiana Life Sciences Association can receive significant discounts—up to 75%—off list prices on goods including lab equipment, office supplies, corporate travel and insurance.
AI tools allow startups to drastically reduce their initial costs
Artificial intelligence is making it less expensive to start and operate a company—and potentially reducing these startups’ reliance on venture funding.
Indianapolis startup bank Generations set to launch early next year with two retail locations
Generations is set to be Indiana’s first minority depository institution—and one of only 153 operating in the United States and its territories. But the bank will be open to anyone.
Nonprofit aims to clothe men reentering the workforce
In Pursuit Of Inc. plans to begin taking referrals early next year from area organizations helping men who are struggling to get their lives together.
OpenAI now worth $500B, possibly making it the world’s most valuable startup
The valuation reflects high expectations for the future of AI technology and continues OpenAI’s remarkable trajectory from its start as a nonprofit research lab in 2015.
Animal-health startup BiomEdit advances poultry antibody, lands $20M in funding, grants
BiomEdit said the disease it’s targeting, avian necrotic enteritis, causes an estimated $6 billion in annual losses worldwide.
Gener8tor’s new Bolt conference set for Indianapolis this fall
The Wisconsin-based startup accelerator is shifting its conference strategy to one large gathering irather than a handful across the U.S., a move expected to expand networking opportunities among investors and entrepreneurs.
Indianapolis-based startup leans on connections to treat brain diseases
Syndeio Biosciences sees burgeoning potential to treat mental health and cognitive conditions, including Alzheimer’s and depression, with therapies that target the almost countless minuscule brain synapses that give people the ability to think and function.
Q&A with IU Innovate’s Julie Heath: Using entrepreneurship as a way to drive Indiana’s economy
IBJ talked with Heath last week during the Global Entrepreneurship Congress at the Indiana Convention Center about what IU Innovates has accomplished in its first two years and what’s next for the effort.
Governor’s IEDC moves raise questions about planned VC growth fund
Almost exactly one year ago, Indiana officials publicly announced a significant entrepreneurial resource the state had been quietly working on for several years—the launch of a $100 million investment fund to help young companies scale up their businesses. A lot has changed since then.
Lesley Weidenbener: Startups deliver big, bold ideas
IBJ strayed from its usual format last week to bring you our annual Innovation Issue, which this year featured 20 startup companies worth watching.
2025 Innovation Issue: What’s a startup? Most say it’s a company that’s young, disruptive and scalable
Even seasoned entrepreneurs and business executives have different takes about exactly what constitutes a startup—or at least a successful one.
2025 Innovation Issue: Startup expert says founders need business skills in addition to a great idea
Rob Mathews, executive director of Ball State University’s Entrepreneurship Center, views leadership and innovation as inseparable attributes for a startup.
Elevate says state funding freeze endangers startups, entrepreneurial community
Commerce Secretary David Adams announced last week that the state had frozen funds earmarked for Elevate Ventures, but he did not outline specific concerns about the nonprofit or its operations.
New lender’s approach will be a first for state
Evansville-based Old National Bank is working on a first-of-its-kind effort: the launch of an Indiana-based bank whose target customers are minorities and those underserved by traditional banks.
Chicago-based venture firm adds Indianapolis-based partner
Chicago-based M25, a venture firm that invests in early-stage Midwestern tech startups, has named local entrepreneur Brian Powers as its Indianapolis-based venture partner.