Sanofi, Glaxo start human trials for COVID-19 vaccine
Two of the world’s biggest vaccine makers, began testing their experimental COVID-19 shot in the first patients on Thursday and aim to start late-stage trials before year-end.
Two of the world’s biggest vaccine makers, began testing their experimental COVID-19 shot in the first patients on Thursday and aim to start late-stage trials before year-end.
Lilly and partner Boehringer Ingelheim published results from a trial showing the drug cut the risk of cardiovascular hospitalizations or death by 25%, compared to placebo in heart failure patients.
Now that the company has closed its $6.9 billion acquisition of the German conglomerate’s animal-health division, it must now swiftly and carefully integrate the two sprawling companies in the midst of a pandemic.
The developers said they have the potential to manufacture up to 100 million vaccine doses by the end of this year and up to 1.3 billion doses by the end of 2021.
President Trump signed four executive orders Friday. One was about importation. The others would direct drugmaker rebates straight to patients, provide insulin and EpiPens at steep discounts, and use lower international prices to pay for some Medicare drugs.
In the past seven years, the drugmaker has received tax breaks worth nearly $40 million in exchange for investing more than $500 million at its Indianapolis properties.
Shares in Elanco rose 2.8% Wednesday morning after the approval was announced, to $24.13 each.
A subsidiary of Swiss drug giant Novartis AG announced plans Tuesday to build a targeted radioligand therapy plant at Purdue Research Park near Indianapolis International Airport.
West Lafayette-based Bioanalytical Systems’ latest executive departure comes amid recent signs of stability, turnaround and growth for a company that just three years ago was on the verge of sinking.
Health and Human Services Secretary Alex Azar called the decision in federal court in Washington, D.C., “a resounding victory” for President Donald Trump’s efforts to open up the convoluted world of health care pricing.
In a major legal setback for President Donald Trump on a high-profile consumer issue, a federal appeals court has ruled that his administration lacks the legal authority to force drug companies to disclose prices in their TV ads.
Researchers in England say they have the first evidence that a drug can improve COVID-19 survival: The cheap, widely available steroid reduced deaths by up to one-third in severely ill hospitalized patients.
Unlike many pharmaceutical startups, which often contract with outside manufacturers to make their drugs, Point Biopharma is spending $25 million to transform a building in Indianapolis where it hopes to handle its own manufacturing as soon as 2023.
The company is one of many across the globe in a mad rush to develop radioligand therapies for cancer treatment—a field that’s expected to see explosive growth.
The Covid-19 pandemic is hampering research across the pharmaceutical industry, including at Indianapolis-based Eli Lilly and Co.
Remdesivir is farther along in testing than many other potential therapies, and the current studies could lead to regulatory approval.
In a deal that could eventually be worth close to a billion dollars, Eli Lilly and Co. is teaming with a British biopharmaceutical company in one of the hottest areas in medical research.
The Food and Drug Administration has given emergency approval to a plan to distribute millions of doses of anti-malarial drugs to hospitals across the country, saying it is worth the risk of trying unproven treatments to slow the progression of the disease in seriously ill coronavirus patients.
Karuna Therapeutics Inc., a publicly traded biopharmaceutical company, is developing a potential blockbuster treatment for schizophrenia that got its start at Eli Lilly and Co. decades ago.
Experts who have studied the so-called “orphan drug” program say the company’s request—and the FDA’s decision to grant it—seem inappropriate given the rapidly expanding threat of the viral outbreak. A financial analyst, though, called Gilead’s request “pretty standard.”